Frequently Asked Questions

Key ingredient: S-equol. Inactive ingredients: dicalcium phosphate, fermented soy germ, silicon dioxide, croscarmellose sodium, magnesium stearate, coating (hypromellose, glycerin, hydroxypropyl cellulose), and microcrystalline cellulose. Contains soy. The soy used to derive S-equol is tested and certified non-GMO.

S-equol is the key ingredient in Equelle. It is a naturally derived compound produced through fermentation of soy germ. Some people also produce it in the gut after eating soy. Equelle uses a patented fermentation process.

The soy used to derive S-equol in Equelle is tested and certified non-GMO.

Equelle is a non-prescription, hormone-free dietary supplement containing naturally derived S-equol. It has been studied for reducing the frequency of hot flashes and muscle aches, and for supporting sleep quality and healthy bones.

As estrogen declines, menopause symptoms can increase. Equelle contains S-equol, which mimics some beneficial effects of estrogen and may help relieve menopause symptoms.

Equelle has been clinically studied for reducing the frequency of hot flashes and alleviating muscle aches. It also supports sleep quality and healthy bones.

Equelle may be suitable for women in menopause or postmenopause who experience symptoms associated with estrogen decline, including hot flashes and muscle aches.

Equelle contains naturally derived S-equol, is produced through a patented process, and is backed by decades of research and four randomized, placebo-controlled clinical trials.

Taking Equelle does not increase estrogen levels. S-equol mimics some actions of estrogen by preferentially binding to estrogen receptor beta. Equelle is free from human and animal hormones.

Equelle’s S-equol is a plant-based compound made by fermenting soy germ. Only trace amounts of soy compounds remain in the finished product.

Equelle’s active ingredient S-equol comes from Japan. The tablets are manufactured in the United States.

Take two tablets daily to maintain S-equol levels during the day and night. Taking them with food may help if you have a sensitive stomach.

Equelle can be taken while menopause symptoms persist. If symptoms subside, you can stop and see whether they return. The source site says no known side effects have been identified from long-term use.

Yes. Equelle tablets can be broken or crushed and taken in liquid or food.

Food is not required. If you have a sensitive stomach, taking Equelle with food may help reduce discomfort.

Clinical trials reported menopause symptom relief as early as one month, with optimal results after two to three months.

S-equol has been studied for safety. Botanical supplements may cause gastrointestinal upset. If you experience stomach sensitivity, take Equelle with food. If you experience other adverse effects, discontinue use and consult your healthcare professional.

The source site describes three double-blind, randomized clinical trials supporting relief of common menopause symptoms, including hot flashes and sleep quality. See the Clinical Results page for study details.

Because Equelle contains calcium, the source recommends taking iron supplements or multivitamins containing iron one to two hours apart and thyroid medication four hours apart. Ask your doctor about these and any other medications.

Speak with your physician to determine what is best for your circumstances.

Speak with your physician to determine what is best for your circumstances.

Equelle contains a small amount of soy, less than a serving of common soy foods.

Equelle is a dietary supplement. The source site states it follows FDA current good manufacturing practice requirements. Dietary supplements are not FDA approved to diagnose, treat, cure, or prevent disease.

No. Trace amounts of soy compounds remain after fermentation, so Equelle should not be taken by anyone with a soy allergy or sensitivity.